Transcription factor regulation of pancreatic organogenesis, differentiation and maturation
نویسندگان
چکیده
منابع مشابه
Regulation of cellular differentiation by tissue specific transcription factor
Tissue specific transcription factors play important roles during cellular differentiation. To regulate cellular differentiation, we paid attention to tissue specific basic helix-loop-helix (bHLH) transcription factors. In this study, we tried to regulate expression of tissue specific transcription factor for induction of cellular differentiation. To regulate expression of transcription factor,...
متن کاملHomeobox transcription factor VentX regulates differentiation and maturation of human dendritic cells.
Dendritic cells (DCs) are specialized antigen presentation cells that play critical roles in the initiation and regulation of immune responses. The molecular determinants of DC differentiation and maturation are target of extensive investigation. VentX is a human homeobox transcriptional factor that regulates proliferation and differentiation of hematopoietic cells. In the current study, we rep...
متن کاملMaturation promoting factor and cell cycle regulation.
Cell cycles in early amphibian embryos are characterized by the absence of G1 and G2 phases. The simple cycle of S phase and mitosis does show similarities with other systems, particularly in the presence of cytoplasmic components advancing nuclei into DNA synthesis and mitosis. Maturation-promoting factor induces nuclear envelope breakdown and subsequent chromosome condensation. Cytoplasmic fa...
متن کاملTranscription factor E2F1 suppresses dendritic cell maturation.
Transcription factor E2F1 has been largely studied as a promoter of S-phase transition in the cell cycle and as a regulator of apoptosis. Recently, E2F1 has been shown to regulate a wide range of genes in response to inflammatory stimulation of macrophages and to contribute to T cell activation in response to pathogens, implicating an extensive immunological role for E2F1. Dendritic cells (DCs)...
متن کاملDifferentiation, maturation, and survival of dendritic cells by osteopontin regulation.
Dendritic cells (DCs) are antigen-presenting cells with the ability to induce primary immune responses necessary in innate immunity and adaptive immunity. Osteopontin (OPN) is a secreted acidic phosphoprotein containing an arginine-glycine-aspartate sequence and has been suggested to play an important role in early cellular immune responses. The interaction between DCs and OPN has not been clar...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Islets
سال: 2015
ISSN: 1938-2014,1938-2022
DOI: 10.1080/19382014.2015.1075687